Key Market Overview:
Automated liquid handling market size was worth over USD 1.3 Billion in 2022 and is estimated to reach over USD 2.4 Billion by 2030, growing at a CAGR of 9.3% during the forecast period (2023-2030).
Automated liquid handling refers to the use of robotic or automated systems to perform various liquid handling tasks in a laboratory setting. These tasks may include dispensing, transferring, mixing, diluting, and other related activities that involve the accurate and precise handling of liquids. Automated liquid handling systems are designed to improve the reproducibility, precision, and efficiency of liquid handling tasks, particularly in high-throughput applications such as drug discovery and genomics research. These systems typically use a combination of hardware and software components, including pipettes, dispensers, robotics, and imaging systems, to automate liquid handling tasks and enable the processing of large volumes of samples with minimal human intervention. Automated liquid handling systems are customized to meet the specific requirements of different applications and also help to reduce the risk of errors, increase productivity, and improve data quality in the laboratory.
The pipetting module is the most critical component of an automated liquid handling system. The pipette head is available as a single-channel pipette or a multi-channel pipette with multiple tips that transfer liquid simultaneously. The volume of liquid completely depends on the type of pipette head, which ranges from a few nanoliters to several milliliters. The software used to control automated liquid handling systems is often designed to be user-friendly, with a graphical user interface that allows users to design and execute liquid handling protocols. The software also includes features that help prevent contamination, such as the ability to track the volume of liquid dispensed, the ability to wash pipette tips between transfers, and the ability to detect and correct for air bubbles in the liquid.
Moreover, such automated liquid handling systems find major usage especially in clinical trials to minimize the risk of contamination by reducing the number of manual steps involved in liquid handling during drug formulations. The rate of a sudden increase in clinical trials in several countries is anticipated to boost the demand for such systems to handle toxic materials with minimal human intervention in terms of reduced likelihood of accidental spills or exposure. For instance, ClinicalTrials.gov, the registry database for clinical trials in the United States, currently lists over 442,000 studies being conducted across all 50 US states and in 221 countries worldwide, according to the US National Library of Medicine. Thus, high deployment of automated liquid handling to reduce the risk of human exposure to hazardous or toxic chemicals and improve worker safety in such clinical trial studies is estimated to support the automated liquid handling market growth during the forecast period.
Automated Liquid Handling Market Coverage
|Market Size in 2030 (USD Billion)
|Workstations, Reagents & Consumables (Tubes and Plates, Reagents Containers, Others
|Automated Liquid Handling Systems, Semi-Automated Liquid Handling Systems
|Serial Dilution, Plate Reformatting, Plate Replication, PCR Setup, High-Throughput Screening, Cell Culture, Whole Genome Amplification, Array Printing, Others
|Fixed Tips, Disposable Tips
|Drug Discovery, Forensics, Clinical Research, Pharmaceutical Development, Cancer & Genomic Research, Bioprocessing/Biotechnology, Others
|By End Use
|Academic & Research Institutes, Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Hospitals, Diagnostic Laboratories, Others
|By Distribution Channels
|Direct Sales, Indirect Sales
|Asia-Pacific [China, Southeast Asia, India, Japan, Korea, Western Asia]
Europe [Germany, UK, France, Italy, Russia, Spain, Netherlands, Turkey]
North America [United States, Canada, Mexico]
Middle East & Africa [GCC, North Africa, South Africa]
South America [Brazil, Argentina, Columbia, Chile, Peru]
|Agilent, Analytik Jena, Anton-Paar, Aurora Biomed, Distek, Elemental Scientific, Ellutia, EST Analytical, Fritsch International, GBC Scientific Equipment, GE Healthcare Life Sciences, Gerstel, Gilson, Hitachi, Hamilton Company, iChrom, Thermo Fisher Scientific, SPT Labtech, QIAGEN N.V., Shimadzu Scientific
The automated liquid handling market is primarily driven by factors such as rising demand for high-throughput screening in drug discovery, growing investments in genomics and proteomics research, and increased adoption of automation in clinical diagnostics and forensic analysis. Moreover, the need for reproducibility and accuracy in liquid handling, increasing demand for miniaturization and automation of laboratory workflows, and the growing focus on reducing operational costs and improving efficiency in the laboratory mainly boost the market growth during the forecast period.
High-end automated liquid handling systems are expensive which hampers access to a large portion of the market. The demand for such equipment typically exceeds the supply which leads to product shortages and inflated prices. Further, high-performance automated liquid handling has a high power consumption that restricts large-scale usage in battery-powered devices. Furthermore, concerns about the accuracy and reproducibility of automated liquid handling systems, particularly for low-volume dispensing, also limit the adoption in certain applications.
The rising demand for automation in emerging markets, particularly in the Asia Pacific and Latin America, in terms of pharmaceutical developments, offers significant growth potential for market players. Furthermore, the growing trend towards personalized medicine and the need for high-throughput screening in drug discovery and development is expected to create lucrative opportunities for automated liquid handling systems. The increasing adoption of robotics and artificial intelligence (AI) in laboratory workflows is also anticipated to offer opportunities for the development of advanced liquid handling systems with the ability to perform complex tasks with high precision and accuracy. Moreover, the scope of integrating automated liquid handling systems with other laboratory technologies such as next-generation sequencing and mass spectrometry is estimated to offer creative opportunities for the development of integrated solutions that streamline laboratory workflows and improve efficiency. Moreover, the emergence of new applications in areas such as single-cell analysis, synthetic biology, and CRISPR gene editing is expected to create new opportunities for the automated liquid handling market.
Automated Liquid Handling Market Segmentation:
The product segment is divided into workstations, reagents & consumables. The workstation segment contributed the largest shares to the market growth in 2022. The increased usage of workstations in manufacturing environments to provide a dedicated space for specific tasks, such as assembly, inspection, and packaging supports segment growth due to the ability to offer consistent and reproducible results, especially in quality control and regulatory compliance applications. Also, the rising usage of workstations in scientific research to provide a dedicated space for specific experiments and processes boosts the demand for workstations that are customized to suit the needs of specific applications such as cell culture workstations or PCR workstations. Moreover, the reagents & consumables segment is also anticipated to contribute substantial shares to the market growth during the forecast period. The increased usage of such high-quality reagents & consumables for molecular biology, cell culture, protein purification, clinical diagnostics, and environmental testing, and others is anticipated to boost the segment growth for achieving accurate and reliable results in such areas and help to accelerate scientific discovery, improve product quality, and ensure the safety of the public.
The type segment is separated into automated liquid handling systems and semi-automated liquid handling systems. The automated liquid handling systems accounted for the largest market share in 2022. The large usage of automated liquid handling systems to screen large numbers of compounds for potential drug candidates boosts the segment growth especially among researchers to identify new treatments for a variety of diseases. Also, the high demand for such automated liquid handling systems in the preparation of DNA and RNA samples for sequencing and analysis in high-throughput genomics research accelerates segment growth in terms of a variety of liquid handling tasks, including dilutions, transfers, and dispensing.
The procedure segment is divided into serial dilution, plate replication, cell culture, PCR setup, high-throughput screening, plate reformatting, array printing, whole genome amplification, others. The serial dilution segment is anticipated to register the fastest CAGR growth during the forecast period in terms of volume and value. The increased focus on large-scale automation of several laboratory research such as drug discovery, clinical diagnostics, and environmental monitoring is estimated to support the demand for serial dilution due to the scope of programming automated liquid handling systems to perform a range of dilutions, from simple two-fold dilutions to more complex dilution series with custom dilution factors in mentioned applications. Moreover, the array printing segment is also estimated to support the market growth in terms of volume. The rising usage of an automated array to help consistently produce large numbers of identical arrays is anticipated to enable researchers to analyze many samples simultaneously by accommodating a variety of substrates and molecules.
The modality segment is bifurcated into fixed tips and disposable tips. The disposable tips segment contributed the largest shares to the market growth in 2022. The high usage in applications with critical high sample purity, such as in PCR or genotyping fuels the demand for disposable tips that are used one time and then discarded to reduce the risk of cross-contamination between samples. The usage of disposable tips results in time conservation as compared to reusable tips due to the reduced need for washing and sterilizing tips between uses. However, fixed tips are also anticipated to contribute significant shares to the market growth during the forecast period. The diverse number of applications in automated liquid handling systems in areas such as molecular biology, cell culture, protein purification, clinical diagnostics, environmental testing, and others is estimated to support the demand for fixed tips in terms of rapid and efficient processing of a large number of samples or reagents.
The application segment is divided into forensics, clinical research, pharmaceutical development, cancer & genomic research, bioprocessing/biotechnology, drug discovery, and others. The pharmaceutical development segment is anticipated to contribute substantial shares to the market growth during the forecast period. The scope of programming automated liquid handling systems to perform a range of tasks, from simple liquid transfers to more complex assays, is anticipated to support the segment demand in terms of high adaptability to the needs of different pharmaceutical development programs. Also, the large usage of automated liquid handling systems to track and store data related to each step of the pharmaceuticals or drug development process is expected to boost the segment growth in terms of a complete record of the overall experiment.
The end-user segment comprises academic & research institutes, pharmaceutical & biotechnology companies, contract research organizations, hospitals, diagnostic laboratories, and others. The pharmaceutical & biotechnology companies segment contributed the largest shares to the market growth in 2022. The increased demand for automated liquid handling systems for simplification of multi-parameter and complex experiments in a reliable, reproducible, and robust manner supports the segment growth in terms of increased aid to highly trained scientists in data analysis and skilled planning of high-throughput screening applications such as genomics-based target discovery and next-generation sequencing. Also, the diagnostic laboratories segment is anticipated to support market growth in terms of value. Automated liquid handling systems are expected to witness high demand in diagnostic laboratories due to the growing need for a range of pumps to perform tasks such as dispensing bodily fluids, dosing reagents, cleaning needles, and eliminating residues in clinical chemistry, haemostasis analysis, immunology, and microbiology.
By Distribution Channel
The distribution channels are segmented into direct sales and indirect sales. The direct sales segment contributed the largest shares to the market growth in 2022. The increased need for personalized service and support from manufacturers to product vendors support the direct sales of automated liquid handling systems. Moreover, such direct sales also result in high-profit margins due to reduced involvement of intermediaries or third-party distributors which allows manufacturers or vendors to sell such automated liquid handling systems at a higher price and retain a larger portion of the profit. Also, the indirect sales segment is estimated to support the market growth in terms of volume. The increased dependence on indirect sales for effective help in sales and distribution via intermediaries or third-party distributors boosts segment adoption among manufacturers or vendors in terms of increased focus on the core activities such as product development and innovation.
The regional segment comprises North America, Asia Pacific, Europe, Latin America, and the Middle East and Africa. North America accounted for the largest share contribution to the market growth in 2022.
The large and established presence of pharmaceutical and biotechnology companies due to high expenditures on healthcare supports the automated liquid handling market demand in the North American region. Moreover, the demand for automated fluid handling systems is expected to increase significantly due to a rising number of drug discovery projects in this region, especially for the screening of vast numbers of compounds. Further, the Asia Pacific region is also anticipated to support market growth in terms of value and volume during the forecast period. The high prevalence of chronic diseases such as cancer, diabetes, and heart disease among the population is expected to support the high need for such automated liquid handling systems for effective screening and development of biopharmaceuticals.
Structured Cabling Market Competitive Landscape:
The automated liquid handling market is highly competitive and includes various companies such as Hamilton Company, Agilent Technologies, PerkinElmer, Inc., and others. The companies offer a wide range of automated liquid handling solutions that cater to various applications and end-users such as academic and research institutes, pharmaceutical and biotechnology companies, and clinical laboratories. The market is characterized by intense competition, rapid technological advancements, and the need for customization to meet the specific requirements of end-users. The major strategies adopted by companies in the market include new product launches, partnerships and collaborations, mergers and acquisitions, and expansion of product portfolios to gain a competitive edge. Listed are market players comprising the latest market concentration–
• Analytik Jena
• Aurora Biomed
• Elemental Scientific
• EST Analytical
• Fritsch International
• GBC Scientific Equipment
• GE Healthcare Life Sciences
• GERSTEL GmbH & Co.KG
• Hamilton Company
• Thermo Fisher Scientific
• PerkinElmer Inc.
• Shimadzu Scientific
• SPT Labtech
• QIAGEN N.V.
• In March 2021, QIAGEN N.V. launched the QIAcube Connect MDx, that is a flexible automated sample processing platform available globally for molecular diagnostic labs in the U.S. and Canada, the European Union, and other markets.
• In November 2021, Anton Paar TriTec launched a new product named Hit 300 that makes nanoindentation technology accessible to small and medium-sized companies along with schools and universities for research and training purposes. The Hit 300 comes with a fully automatic ability to measure up to 600 samples per hour. The device is also easy to operate, with setup taking just 15 minutes and enrollment less than an hour due to the intuitive design.
• In February 2022, SPT Labtech revealed a 4-in-1 automated liquid handling system called the apricot DC1 at the SLAS 2022 International Conference and Exhibition in Boston. The system is designed to help laboratories simplify their daily pipetting procedures across various applications by providing a compact automated pipettor.